Bisphosphonate 복용환자에서 임플란트를 식립하는 것이 정당한가?
Implant placement under bisphosphonate therapy
박원서, 김형준, 정원윤, 김기덕, 윤희정,
소속 상세정보
박원서 ( Park Won-Se ) - 연세대학교 치과대학 통합진료학과
김형준 ( Kim Hyung-Jun ) - 연세대학교 치과대학 구강악안면외과학교실
정원윤 ( Chung Won-Yoon ) - 연세대학교 치과대학 구강생물학교실
김기덕 ( Kim Ki-Deok ) - 연세대학교 치과대학 통합진료학과
윤희정 ( Yun Hee-Jung ) - 연세대학교 치과대학 통합진료학과
KMID : 1025720120310010001
Abstract
Bisphosphonate is a group of drug that inhibits the function of osteoclast and used for multiple myeloma, Paget’s disease, metastatic malignant bone disease. Recently the use of bisphosphonate on osteoporosis increasing so the side effect is also increasing even though it is relatively safe drug. The complication includes gastrointestinal disturbances, esophageal cancer, atypical fracture of femur, and osteonecrosis of the jaw. Bisphosphonate related osteonecrosis of the jaw (BRONJ) is mostly evoked by invasive bone surgery like tooth extraction. BRONJ associated with dental implant is rare, however, as the use of bisphosphonate increase, BRONJ cases with dental implant are increasing. In this article, we will describe the considerations during dental implant treatment for patient under bisphosphonate therapy.
키워드
Implant; Osteonecrosis; Failure; Bisphosphonate; Jaw
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